Diallyl disulfide

Research use only, not for human use.

Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.

Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.

Cell Viability Assay Cell Line:HT-29 cells Concentration:30, 60, 120 and 240 μM Incubation Time:12, 24, 48 h Result:Suppressed HT-29 cell growth by 5.3, 23.1, 45.6 and 68.3% with 30, 60, 120 and 240 μM for 24 h, respectively.Cell Cycle Analysis Cell Line:HT-29 cells Concentration:30, 60, 120 μM Incubation Time:24 hResult:The percentage of cells in the G2/M-phase was found to be 23.6, 25.9, 39.7 and 61.0% with 30, 60, 120 and 240 μM, respectively.RT-PCR Cell Line:HT-29 cells Concentration:120 μM Incubation Time:Result:The mRNA levels of ARPC3, SPINT2, SOD1, p21 and TACSTD2 were 3.52-, 7.98-, 15.6-, 13.47- and 5.92-fold higher than those in the primary cultured cells, respectively.

Animal Model:Male C57BL6/J mice (6-8 weeks)Dosage:40, 80 mg/kg Administration:IP; pre-treatment 1 h before a single LPS injection (100 μg/kg)Result:Prevented LPS-induced increases in immobility time in the TST and FST in mice.

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Apoptosis

IL Receptor

IL Receptor|NF-κB|NOS

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2179-57-9

146.3

C6H10S2

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (683.67 mM)

C=CCSSCC=C

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(-20℃)

With Ice Pack

≥ 2 years